Synthesis of bis(indolyl)methanes using La(OTf)3 as an efficient catalyst under solvent-Free condition

Jagadeesh Kumar Ega
Department of Chemistry, Kakatiya University, Warangal Urban,TS-506009 , IN

Kavitha Siddoju
Department of Chemistry, Kakatiya University, Warangal Urban,TS-506009 , IN

Rohini . Malipeddi
Department of Chemistry, Kakatiya University, Warangal Urban,TS-506009 , IN

Keywords: bis indolyl methane, La(OTf)3, substituted benzaldehyde, MWI

Abstract

In this present protocol affords bis(indolyl)methanes in excellent yields employing mild, efficient, catalyst La(OTf)3. Reaction of benzaldehyde and indole was considered as amodel reaction. The reaction mixture was irradiated at 120 ºC and 450 W in microwave oven for appropriate time to give desired products 3a-n.All the products were further confirmed by spectral analysis.

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